Certified Wound Ostomy Nurse (CWON) Practice Test

What can cause bullous lesions?

1. Infectious agents only

2. Genetic factors and autoimmune disorders

3. Trauma exclusively

4. Only allergic reactions

The correct answer is: Genetic factors and autoimmune disorders

Bullous lesions, which are fluid-filled blisters on the skin, can arise from various causes, including genetic factors and autoimmune disorders. Autoimmune conditions, such as pemphigus vulgaris and bullous pemphigoid, lead to the body mistakenly attacking its own tissues, resulting in the formation of blisters. Additionally, certain genetic disorders can predispose individuals to form bullae due to structural weaknesses in the skin. While it is true that infectious agents, trauma, and allergic reactions can also cause bullous lesions, the range of conditions captured by genetic factors and autoimmune disorders comprehensively encompasses significant underlying mechanisms for their development. Focusing solely on infectious agents, trauma, or allergic responses would overlook critical pathological processes that contribute to the formation of bullous lesions in various clinical settings. Therefore, the answer highlighting genetic factors and autoimmune disorders appropriately reflects the diverse etiology of bullous lesions.