Certified Wound Ostomy Nurse (CWON) Practice Test

What factor influences the antibacterial effectiveness of Manuka honey-based dressings?

1. The type of wound treated

2. Application method

3. Concentration

4. The duration of exposure

The correct answer is: Concentration

The antibacterial effectiveness of Manuka honey-based dressings is significantly influenced by the concentration of the honey used in the dressing. Manuka honey is noted for its unique antibacterial properties, which stem from its high content of methylglyoxal (MGO) and other bioactive compounds. The higher the concentration of these components, the greater the antibacterial activity exhibited against various pathogens. Concentration plays a critical role because it determines how much of the active antibacterial agents are available to inhibit microbial growth. Lower concentrations may not provide sufficient antibacterial activity, potentially leading to inadequate wound healing. Conversely, optimal concentrations are necessary to harness the full therapeutic potential of Manuka honey while minimizing any potential adverse effects. Additionally, while factors such as the type of wound treated, application method, and duration of exposure can also affect the overall healing process and effectiveness of a dressing, they do not directly influence the inherent antibacterial properties of the Manuka honey itself as concentration does. Concentration is the key factor in ensuring effective antimicrobial action against infection-promoting microorganisms in wound environments.