Certified Wound Ostomy Nurse (CWON) Practice Test

What is granulation tissue made of?

1. Generalized redness

2. Loose, stringy, nonviable tissue

3. Serous fluid trapped under skin greater than 0.5cm in diameter

4. Capillary networks, collagen, and other connective substances

The correct answer is: Capillary networks, collagen, and other connective substances

Granulation tissue is a critical component of the wound healing process, formed during the proliferative phase following injury. It is characterized by the presence of new blood vessels (capillary networks), collagen fibers, and various other connective tissues. This tissue typically appears as a reddish, bumpy surface that is vital for wound repair as it provides a scaffold for cell migration and is necessary for the development of new tissue. The capillary networks are crucial as they deliver oxygen and nutrients essential for healing and also remove waste products from the wound site. Collagen, produced by fibroblasts, provides structural support and strength to the new tissue, helping to close the wound. Therefore, the composition of granulation tissue plays an important role in ensuring effective wound healing and restoration of skin integrity. The presence of these components distinguishes granulation tissue from other types of tissue and fluid seen in wounds.