Certified Wound Ostomy Nurse (CWON) Practice Test

What is one mechanism of action (MOA) of NPWT?

1. Promotes excessive granulation without limitation

2. Creates a moist environment that delays healing

3. Reduces bacterial loads and inflammatory agents

4. Utilizes high pressure to stimulate circulation

The correct answer is: Reduces bacterial loads and inflammatory agents

The mechanism of action of Negative Pressure Wound Therapy (NPWT) that is most relevant is its ability to reduce bacterial loads and inflammatory agents. NPWT works by applying sub atmospheric pressure to the wound, which helps to draw out excess fluid and exudate. This process not only removes harmful bacteria and debris from the wound site but also minimizes the risk of infection, promoting a healthier healing environment. Moreover, by reducing edema and improving local perfusion, NPWT can help to decrease inflammatory agents that may impede the healing process. This environment is conducive to the formation of granulation tissue, essential for proper wound healing. The other options, while containing elements that may seem plausible, do not accurately reflect the primary functions or benefits of NPWT. Excessive granulation tissue is a concern mainly in wounds not appropriately managed. A moist environment is critical for healing, but delaying healing contradicts the primary goal of NPWT, which is to promote healing through a controlled moist environment. Lastly, despite NPWT creating negative pressure, it does not utilize high pressure; rather, it creates a vacuum that aids in blood flow rather than stimulating circulation through high pressure.