Certified Wound Ostomy Nurse (CWON) Practice Test

What is the primary indication for using becaplermin gel?

1. For all types of wounds

2. Only for clean, noninfected neuropathic wounds

3. For infected wounds

4. For post-surgical wounds

The correct answer is: Only for clean, noninfected neuropathic wounds

Becaplermin gel is specifically designed for use in clean, noninfected neuropathic wounds, particularly in patients with diabetic ulcers. The primary mechanism of becaplermin is its role as a recombinant human platelet-derived growth factor (rhPDGF), which aids in the healing process by promoting cell migration and proliferation, especially in wounds where there is a deficiency of this growth factor. The effectiveness of becaplermin gel is maximized when applied to wounds that are clean and noninfected. Infected wounds would not only render this treatment ineffective but could also exacerbate the infection. Similarly, the gel is not meant for post-surgical wounds unless they fall under the category of noninfected neuropathic ulcers. Its use is also restricted to certain types of ulcers; therefore, it is not applicable for all types of wounds generically. The careful selection of appropriate wounds for treatment with becaplermin gel underlines the importance of understanding wound characteristics and the underlying conditions they represent, ensuring that the method of healing promoted is suitable for the patient's specific situation.