Certified Wound Ostomy Nurse (CWON) Practice Test

What occurs approximately five days after a dermal loss injury during the epithelial cell proliferation and migration stage?

1. A layer of fluid separates the epidermis from the dermis

2. Collagen synthesis begins immediately

3. Blood vessels retract

4. Epithelial cells stop migrating

The correct answer is: A layer of fluid separates the epidermis from the dermis

During the epithelial cell proliferation and migration stage, which typically occurs around five days following a dermal loss injury, the healing process involves the formation of a new epithelial layer over the wound. At this stage, one of the notable phenomena is the presence of a layer of fluid that can separate the epidermis from the dermis. This fluid typically consists of plasma and inflammatory exudate, and serves several purposes: it facilitates the movement and migration of epithelial cells, provides a moist environment that is conducive to healing, and helps to transport necessary nutrients and growth factors to the site of injury. This fluid layer also aids in the softening of the scab or crust, making it less adherent and allowing for easier migration of the epithelial cells. Thus, the presence of this fluid is a critical component of the healing process during epithelial cell proliferation and migration, highlighting its role in wound healing.