Certified Wound Ostomy Nurse (CWON) Practice Test

Which body areas are most commonly affected by calciphylaxis?

1. Arms and shoulders

2. Thighs and buttocks

3. Head and neck

4. Hands and feet

The correct answer is: Thighs and buttocks

Calciphylaxis is a rare but serious condition primarily observed in patients with renal impairment, particularly those undergoing dialysis. It is characterized by calcification of small blood vessels, leading to painful skin ulcers and necrosis. The body areas that are most commonly affected include the thighs and buttocks, where adipose tissue can become involved and where blood supply may be more compromised. This specific localization is important as it clarifies the typical presentation of calciphylaxis. The skin in these areas is also less vascular compared to other regions, which may contribute to the formation of ischemic lesions. Understanding this aspect helps in the early identification and potential management of the condition, emphasizing the need for vigilance in patients at risk, such as those with end-stage renal disease.